My laboratory studies radiation carcinogenesis and biologically augmented radiotherapy. I received my  undergraduate degree from the University of Chicago and earned a doctoral degree in experimental pathology from the University of California, San Francisco. I  conducted postdoctoral research on extracellular matrix mediated functional differentiation with Mina Bissell at the Lawrence Berkeley National Laboratory (LBNL). I then joined LBNL as a staff scientist, where I rose from postdoctoral fellow to Senior Scientist and Associate Director of the Life Sciences Division. I joined New York University School of Medicine in 2008 as Director of Radiation Biology in the Department of Radiation Oncology. I  moved to UCSF as Professor and Vice Chair of Research in the Department of Radiation Oncology in 2015.